This content was reviewed and approved for its accuracy by Professor Frank Joseph

Photograph of Professor Frank Joseph, weight loss expert for myBMI

It it Possible to Overdose on Semaglutide?


It’s possible to overdose on any medicine. Semaglutide isn’t an exception to this.


However, if you follow the instructions, it should be easy to avoid an accidental overdose.


Semaglutide comes as one pen that contains four doses.


This means that a pen should last you a month.


When you twist the dial on the end of the Semaglutide pen, it should stop at the maximum single dosage allowed. 


This is generally 0.25mg, 0.5mg, or 1.0mg depending on which pen you’re using. Only the selected amount will be released into your body.


As long as you don’t inject yourself again, you shouldn’t overdose on Semaglutide.



With Semaglutide, it’s also important to stick to the titration period and not increase your dose too soon.


This can sometimes cause unpleasant side effects and pain or discomfort.


If you find that you’re still hungry on your current dose, you should speak to your prescriber at your next consultation.


They may recommend increasing your dose depending on how long you’ve been taking it for.



If you do inject too much Semaglutide by mistake, you might notice increased nausea or gastrointestinal problems.


As most people that take Semaglutide in the UK are on a maximum dose of 1.0mg weekly, overdose shouldn’t be too harmful if it does happen.


2.4mg weekly Semaglutide injections have recently been released in the USA for weight loss.


This is currently 140% more than the maximum dose for *Semaglutide.



However, if you do inject too much Semaglutide and experience adverse effects, you should contact your GP for advice.


If it’s out of hours and you require medication for your side effects, you should call 111 and explain the situation.



If you do end up taking too much Semaglutide, you might experience some of the following symptoms:

If you do experience any of these after an overdose of Semaglutide, you should make an urgent appointment with a doctor.


It can sometimes be easy to overdose on Semaglutide if you’ve forgotten that you’ve already taken your injection.


To combat this, we recommend keeping it in the original box.


On each box of Semaglutide, a dosing calendar is printed under the lid


You should write the date in these squares when you inject so that you can see at a glance if you’ve already taken it or not.


You could also try marking it in your phone on a to-do list and checking it off once you’ve injected.

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